The causes of patient falls are complex and, as is the case with most adverse events, are typically conditioned by the simultaneous occurrence of multiple unfavorable determinants that cumulatively lead to a patient fall. Studies indicate that in nearly half of cases, hospital falls result from the realization of 3 to 5 fall risk factors. Therefore, effective fall prevention in healthcare facilities requires a comprehensive understanding of all these factors. It is generally accepted that proper identification of risk factors in hospitals and implementation of appropriate measures addressing these factors can prevent 20% to 30% of falls in hospitals. Fall prevention requires both systemic and individual-level interventions. Awareness among healthcare professionals, patients, and their caregivers of the conditions associated with increased fall risk, as well as knowledge of hospital wards and areas within healthcare facilities where falls are most likely to occur, are fundamental elements for improving patient safety. Effective fall prevention necessitates collaboration between medical professionals and architects based on scientific evidence, enabling the creation of safe hospitalization conditions for patients and minimizing the occurrence of adverse events, including falls.