The vision of the traditional hospital as a cold, sterile and inert environment is proving increasingly inadequate in the light of medical research, environmental psychology and architecture. The modern design of hospital spaces must take into account not only functionality and technology, but also the psycho-physical needs of human beings. The aim of this article is to show the role that the appropriate design of hospital spaces plays in the healing process, improving patient wellbeing and supporting the efficiency of medical staff. Two key approaches are discussed in the article: ergonomics (from a holistic perspective) and biophilic design. The authors provided practical advice on how to implement these concepts in hospital zones, and information that should be paid special attention to during design. The article provides insight and inspiration for architects, interior designers and healthcare decision-makers, highlighting the importance of an interdisciplinary, sustainable and humanistic approach to creating healthcare environments.